The nearest airports are: Milano Malpensa (23 km from Varese), Milan Linate (80 km) and Orio al Serio International Airport (106 km).

The train station is served by the national railway company, Trenitalia, and by the interregional company Trenord.

Lombardy is easy to get by car, motorbike and campervan, due to an important road network. Varese is located on the A8, with two exits.

Here is the network of motorways:
A8: a four-lane motorway starting from Milan and Lainate and getting to Varese in a three-lane freeway.
A9: a motorway starting from Lainate to Ponte Chiasso and Switzerland, passing through Saronno and Como.
E62: which drives through Gallarate.
A60: a national motorway managed by the Autostrada Pedemontana Lombarda S.P.A. It is a ring road which drives through the southern suburbs of the city.

CTPI manages local public transport services in Varese and in the south-eastern zone of the province. The goal of the company is to offer passengers a safe and efficient transport service, increasing the efficience of the structures and decreasing the environmental impact.